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Rheumatoid Arthritis News

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Compared with placebo, a team of researchers found that patients taking low-dose methotrexate (LD-MTX) experienced a variety of adverse events (AEs). They identified elevations in risks for skin cancer and gastrointestinal, infectious, pulmonary, and hematologic AEs. However, the authors noted in…
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By Reuters Staff NEW YORK (Reuters Health) - Patients with rheumatic diseases who are on tumor-necrosis-factor inhibitor (TNFi) therapy can safely receive the live varicella zoster vaccine, without risking vaccine-related infection, a new study suggests. "Because patients with rheumatic diseases…
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Polypharmacy can predict clinical outcomes among persons with rheumatoid arthritis, according to results of a new study. The researchers evaluated data of 22,005 patients with RA enrolled in the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis (BSRBR-RA), an ongoing…
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According to recent study findings published online in Annals of the Rheumatic Diseases, the recombinant zoster vaccine, as well as others, are associated with an increased risk of gout flares.   “The recombinant zoster vaccine containing a strong non-aluminium adjuvant is associated with…
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Opioids are often prescribed to individuals with acute gout who are discharged from an emergency department (ED), according to study findings. The researchers evaluated data from the Lifespan electronic health records system on 456 individuals with a primary diagnosis of gout who were discharged…
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Patients with ankylosing spondylitis (AS) are being prescribed opioids at a “concerning” rate, according to the researchers of a new study. To reach this conclusion, the researchers identified participants from the Truven MarketScan database from between January 1, 2012, and March 31, 2017. The…
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Secukinumab is an effective and safe long-term treatment for ankylosing spondylitis (AS), according to final results of the 5-year, phase 3 MEASURE 1 extension trial presented at the ACR/ARHP Annual Meeting. Other than anti-tumor necrosis factor (anti-TNF), secukinumab—a fully human monoclonal…
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By Gene Emery (Reuters Health) - Hoping to tap the anti-inflammatory powers of methotrexate, researchers have failed to show that a low-dose of the drug, already used to fight cancer and arthritis, can reduce the risk of heart attack or stroke. The treatment, detailed Saturday at the American…
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Researchers from the University of Dundee in the United Kingdom have identified a correlation between a mutational signature in cutaneous squamous cell carcinoma and length of treatment with azathioprine. Azathioprine, an immunosuppressive therapeutic, is commonly used for the treatment of…
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Tumor necrosis factor (TNF) inhibitors were not associated with an increased risk for cancer recurrence among patients with rheumatoid arthritis (RA), according to the findings of a recent study. The population-based cohort study included 467 patients who initiated TNF inhibitors between 2001 and…
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