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The deep vein thrombosis (DVT) prophylaxis rates among patients admitted for inflammatory bowel disease (IBD) flares are suboptimal, according to new research presented at the 2019 Advances in Inflammatory Bowel Diseases (AIBD) Meeting. The rate of venous thromboembolisms (VTE) pharmacologic…
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In spite of some limitations to our current knowledge of how diet affects inflammatory bowel disease (IBD), there are some key pieces of guidance that clinicians can give to their patients based on current evidence, reported James Lewis, MD, of the University of Pennsylvania in Philadelphia, at the…
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By Megan Brooks NEW YORK (Reuters Health) - Proton-pump inhibitors, metformin and several other commonly used drugs markedly alter the taxonomic structure and metabolic function as well as antibiotic-resistance genes in the gut microbiome, according to a study from the Netherlands. The changes…
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Use of gastric acid inhibitors is significantly associated with the likelihood of anti-allergic medications, according to the results of a recent study. Previous observational and animal studies have shown a relationship between gastric acid suppression and allergy, but how gastric acid inhibitors…
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By Lorraine L. Janeczko NEW YORK (Reuters Health) - Patients taking oral proton pump inhibitors (PPIs) may be at increased risk of hip fracture, a meta-analysis of observational data suggests. "Physicians should, therefore, exercise caution when considering a long-term PPI treatment to their…
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By Lorraine L. Janeczko NEW YORK (Reuters Health) - Short-term proton-pump inhibitor (PPI) therapy has no clinically meaningful effect on bone turnover, a new study suggests. PPIs have been linked with osteoporotic fractures, but whether they directly cause osteoporosis remains unclear,…
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By Will Boggs MD NEW YORK (Reuters Health) - Men and women with inflammatory bowel disease (IBD) have a significantly increased risk of sexual dysfunction, according to a new meta-analysis. "As people get older, the prevalence of sexual dysfunction increases due to disturbance of hormones," said…
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By Megan Brooks NEW YORK (Reuters Health) - The choice of anticoagulant and proton-pump inhibitor (PPI) cotherapy may affect the risk of upper gastrointestinal-tract bleeding in the elderly, according to a large retrospective study of Medicare beneficiaries. The analysis included more than 1.6…
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By Gene Emery (Reuters Health) - Giving intensive care unit (ICU) patients a proton-pump inhibitor (PPI) to prevent gastrointestinal bleeding does not seem to affect mortality, according to a European trial of nearly 3,300 adults. The 90-day death rate was 31.1% with 40 mg of the PPI pantoprazole…
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New prescriptions of proton pump inhibitors (PPIs) are typically appropriately prescribed for patients with gastroesophageal reflux disease (GERD), but physicians often fail to discuss lifestyle changes with their patients, according to new findings. Because long-term use of PPIs may lead to…
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