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Infection Prevention News

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Study findings posted online in Critical Care Medicine, show that corticosteroid use among individuals with influenza may increase both mortality and hospital-acquired infection. “Corticosteroids may be beneficial in sepsis, but uncertainty remains over their effects in severe influenza,” study…
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By Will Boggs MD NEW YORK (Reuters Health) - The VXA-A1.1 oral influenza vaccine was well tolerated and provided protective immunity against virus shedding similar to that of intramuscular inactivated influenza vaccine (IIV), in a phase II trial. "An oral influenza vaccine would make a big impact…
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The predominance of A(H3N2) clade 3C.3a viruses during the latter part of the 2018-2019 influenza season was associated with a decrease in vaccine effectiveness, according to results of a new study. According to the study authors, the findings support the A(H3N2) vaccine component update for the…
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Authors of a new study have used their findings to develop a clinical decision guideline for influenza testing. The guideline was formulated in an effort to aid clinicians in determining which adult emergency department (ED) patients, who are eligible to receive antiviral treatment, should be…
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The influenza season has started earlier in 2019 than it has in 15 years, with a significant prevalence of illness in the South. The increased activity is being driven mostly by the influenza B/Victoria viruses, which normally appear later in the season. “Activity is being caused mostly by…
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By Marilynn Larkin NEW YORK (Reuters Health) - In patients with rheumatoid arthritis (RA), a high-dose trivalent inactivated influenza vaccine (HD-TIV) is safe and potentially more immunogenic than a standard-dose quadrivalent vaccine (SD-QIV), a randomized controlled, active-comparator trial…
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By Julie Steenhuysen (Reuters) - Roche's influenza treatment Xofluza, a one-dose pill that can clear flu symptoms within days, may cause a mutation of the virus that leads to drug resistance, researchers reported on Monday. Results of their study suggest that common flu strains can quickly…
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By Will Boggs MD NEW YORK (Reuters Health) - An influenza-vaccine candidate targeting the hemagglutinin (HA) stalk elicits cross-reactive antibodies in healthy human adults, according to interim results of a phase 1 clinical trial. "This was the first time a rationally designed universal-…
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Insurance, health care, and employment status play a role in vaccine hesitancy among adults in the United States, according to new research. “Understanding barriers to influenza vaccination can help the development of interventions to reduce influenza vaccine hesitancy, increase vaccination, and…
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By Anne Harding NEW YORK (Reuters Health) - Influenza-season severity and vaccine effectiveness (VE) do not appear to affect flu-vaccination rates in children, according to new research. Dr. Melissa S. Stockwell of NewYork-Presbyterian/Columbia University Irving Medical Center in New York City…
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