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Ovarian Cancer News

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Using whole-exome sequencing, researchers have identified a handful of non-BRCA predisposition genes for breast and ovarian cancer. They published their findings online August 16, 2018, in JAMA Oncology.   “The results of this large-scale exome sequencing of patients and controls shed light on…
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Medically underserved Medicare beneficiaries with breast cancer or ovarian cancer rarely receive BRCA tests, which often help with health-related decision-making, according to a research letter published online in JAMA. According to the researchers, women with ovarian cancer, who test positive…
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A class of antitumor compounds known as HDAC inhibitors offer potential for the treatment of ovarian cancer with mutations in the ARID1A gene. Researchers outlined their rationale in a paper published online in Cell Reports. Already approved by the US Food and Drug Administration (FDA), HDAC…
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Currently used in melanoma treatment, BRAF inhibitors may also be an effective treatment for women with low-grade serous ovarian cancer with a tumor mutation in the BRAF gene, according to a study published online in JCO Precision Oncology. Researchers came to their findings after identifying 65…
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According to a recent study published online in Nature, researchers have identified molecular means by which some cancers caused by errors in the gene BRCA1 evade treatment by PARP inhibitors. It is estimated that roughly 288,000 new cases of breast and ovarian cancer will be diagnosed in this…
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A recent commentary in JAMA Oncology outlined the creation of the ASCO comprehensive cost of care task force to help physicians and patients tackle the increasing imbalance in health care costs and health coverage.  Joshua D Palmer, MD, of the James Cancer Hospital and Solove Research Institute at…
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A study presented at the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting found that although minimally invasive hysterectomy surgery for ovarian cancer reduced costs and morbidity, it also significantly decreased survival among a certain subset of patients. “Surgery is the primary…
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A study presented at ASCO 2018 found that telehealth-based genetic counseling and mandatory discussion of genetic counseling referral at the time of treatment planning improved utilization of genetic counseling for ovarian cancer. “Genetic counseling is recommended for all women diagnosed with…
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Recent research in the International Journal of Gynecological Cancer compared the cost-effectiveness of neoadjuvant chemotherapy versus primary debulking surgery for patients with ovarian cancer. “Neoadjuvant chemotherapy versus primary debulking surgery for advanced epithelial ovarian cancer…
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An Interview with Don S Dizon MD FACP, FASCO, Director of Women's Cancers at the Lifespan Cancer Institute. What is the burden of ovarian cancer? Can you give an overview of this patient population?  Ovarian cancer is diagnosed in about 20,000 women annually in the United States; it makes it the…
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