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Depressive symptoms and altered use of public transportation occurred a decade before diagnosis of late-onset Parkinson disease in a cohort of patients, according to a study published in Parkinsonism & Related Disorders.  “Thanks to the very long-term follow-up of the PAQUID population-based…
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Nearly a third of patients with Parkinson disease and related conditions who lived at home before percutaneous endoscopic gastrostomy (PEG) were discharged to nursing or care homes after the procedure, according to a study published in the journal Movement Disorders Clinical Practice. “PEG can…
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Individuals with Parkinson disease (PD) who have symptoms of anxiety, depression, or apathy may experience worse executive functioning, according to a new study. And individuals with PD and anxiety may be especially likely to experience worse executive functioning if they have mild cognitive…
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By Reuters Staff NEW YORK (Reuters Health) - Apomorphine sublingual film significantly reduces off episodes in patients with Parkinson's disease, according to results of a phase 3 study. As many as 90% of patients with Parkinson's disease receiving chronic levodopa treatment develop motor…
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By Linda Carroll (Reuters Health) - A small study finds that some people lose their ability to swim when their Parkinson's disease is treated with deep brain stimulation. Researchers identified nine cases of Parkinson's patients who effectively forgot how to swim after having a deep brain…
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Patients with Parkinson disease (PD) with mild disease severity can attenuate off-state motor signs by performing at-home aerobic exercise, according to results of the Park-in-Shape trial. To conduct the double-blind trial, the researchers recruited 139 sedentary patients with PD from an…
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In people with Parkinson disease, aerobic exercise appears to increase both caudate dopamine release and ventral striatal activation, according to a study published online in the journal Movement Disorders.  “Aerobic exercise alters the responsivity of the ventral striatum, likely related to…
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In people with Parkinson disease, moving to music rather than metronomes better supported entrainment and control, according to a study published online in the journal Parkinson’s Disease. “These findings provide possibilities for direct application to therapeutic approaches for motor…
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The frequency of subthalamic deep brain stimulation as well as the location of electrode contacts can affect speech in patients with Parkinson’s disease, according to a study published online in Parkinsonism & Related Disorders. “Speech disorders, including stuttering and hypophonia, have been…
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Researchers recently sought to identify mechanisms that sustain gait improvement among patients with Parkinson disease (PD) and found that cueing strategies, which include reshaping of sensorimotor rhythms and fronto-centroparietal and temporal connectivity, are useful.   “Rhythmic Auditory…
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