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Reducing Blood Infections Associated With a Central Line

June 14, 2016

A central line infection prevention bundle lowered central venous catheter (CVC) dwell time and central line–associated bloodstream infections among newborns in a study from researchers in Australia.

The bundle included CVC insertion, CVC maintenance, an education program for hospital staff, and ongoing feedback and surveillance.

Dr. Rowena McMullan and Dr. Adrienne Gordon, the Royal Prince Alfred Hospital Women and Babies and the University of Sydney in Australia, examined data collected from newborn infants with CVCs who were admitted to the neonatal intensive care unit.

The purpose of this retrospective cohort analysis was to ascertain the central line infection prevention bundle’s effectiveness and to pinpoint areas that need improvement.

Researchers collected data at baseline and after bundle implementation. They focused on clinical characteristics, CVC use, and infection.

Findings revealed that central line–associated bloodstream infections were significantly reduced after bundle implementation (1.2/1000 central line-days vs. 11.5/1000 central line-days. Further, the authors reported that overall CVC dwell time decreased among the infants (6 days vs. 7.3 days; P=.0004).

This study was published online in Infection Control & Hospital Epidemiology.


-Meredith Edwards White



McMullan R, Gordon A. Impact of a central line infection prevention bundle in newborn infants. Infect Control Hosp Epidemiol. 2016 Jun 13. [Epub ahead of print]


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