- ALTC

Volume
17

FEATURES

Richard Bedlack, MD, PhD Activity Medical Director Associate Professor of Neurology Duke University School of Medicine Durham, NC

Pathophysiology How Does Diabetes Mellitus Cause Nerve Damage? Although the pathophysiology of diabetic neuropathy is unclear, most experts believe that hyperglycemia is the cause of the nerve damage in DPN.48 Hyperglycemia causes increased levels of intracellular glucose in nerves, leading to saturation of the normal glycolytic pathway.49 Nevertheless, different neuropathies may have different (and perhaps overlapping) mechanisms; for example, with focal or asymmetrical diabetic neuropathy syndromes, vascular injury or autoimmunity may play more important roles | Read More
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Richard Bedlack, MD, PhD Activity Medical Director Associate Professor of Neurology Duke University School of Medicine Durham, NC

No single test can definitely diagnose diabetic peripheral neuropathy, and clinical judgment must play a role. | Read More
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Richard Bedlack, MD, PhD Activity Medical Director Associate Professor of Neurology Duke University School of Medicine Durham, NC

One of the most frequent microvascular complications of type 2 diabetes is diabetic neuropathy. | Read More
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